At last the St. Cecilia Community was able to stand alone. Her life had been one of long suffering. She had fought the good fight and had gained the victory. (Mother Frances Walsh; Annals of St. Cecilia Congregation, 1860-1881)

The twentieth century began with both prosperity and trial, as work in the apostolate flourished and new schools were added. Once again war and economic depression revisited the Sisters of St. Cecilia. The mark of the cross did not result in disaster, however, and was mitigated by the powerful presence of Divine Providence. Some highlights of the time period follow.

Through two World Wars and the Great Depression, the Dominican Sisters of Nashville lived the religious life with a characteristic consistency and a tangible spirit of sacrifice. They expanded in numbers of sisters and reached thousands of students with the opening of numerous schools. Simplicity, hospitality and devotion were the hallmarks of this small southern community. Next to her larger northern counterparts, the Congregation was outside of the mainstream, diminutive and not well-known. Since that time the Congregation has spoken on behalf of religious life and authentic renewal.  In the years that followed the Second Vatican Council, the guidance of the Holy Spirit provided strong leadership and enabled St. Cecilia to respond to the call of Vatican II with a voice that was clear and unequivocal.